Grik1 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN507324
Grik1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN507324 is the updated version of KN307324.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Grik1 |
Locus ID | 14805 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001346964, NM_010348, NM_146072 |
Synonyms | A830007B11Rik; D16Ium24; D16Ium24e; GluK1; GluK5; Glur-5; Glur5; Glurbeta1 |
Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA201736 | Grik1 CRISPRa kit - CRISPR gene activation of mouse glutamate receptor, ionotropic, kainate 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.