Mouse Cxcl1 activation kit by CRISPRa

CAT#: GA201749

Cxcl1 CRISPRa kit - CRISPR gene activation of mouse chemokine (C-X-C motif) ligand 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cxcl1
• Locus ID: 14825
• Kit Components:

  GA201749G1, Cxcl1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201749G2, Cxcl1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201749G3, Cxcl1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008176
• Synonyms: Fsp; gro; Gro1; KC; Mgsa; N51; Scyb1
• Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]