Mouse Hnrnpk activation kit by CRISPRa

CAT#: GA201939

Hnrnpk CRISPRa kit - CRISPR gene activation of mouse heterogeneous nuclear ribonucleoprotein K

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hnrnpk
• Locus ID: 15387
• Kit Components:

  GA201939G1, Hnrnpk gRNA vector 1 in pCas-Guide-CRISPRa

  GA201939G2, Hnrnpk gRNA vector 2 in pCas-Guide-CRISPRa

  GA201939G3, Hnrnpk gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301340, NM_001301341, NM_001301343, NM_001301344, NM_001301345, NM_025279, NM_001360490, NM_001360491, NM_001360493, NM_001360494, NM_001360495, NR_153501, NR_153502, NR_153503, NR_153504
• Synonyms: Hnrpk; KBBP; NOVA
• Summary: The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]