Mouse Hoxa2 activation kit by CRISPRa

CAT#: GA201945

Hoxa2 CRISPRa kit - CRISPR gene activation of mouse homeobox A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hoxa2
• Locus ID: 15399
• Kit Components:

  GA201945G1, Hoxa2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201945G2, Hoxa2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201945G3, Hoxa2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010451
• Synonyms: AI324701; Hox-1.11; HOX1.11
• Summary: This gene is located in a cluster of developmentally and temporally regulated genes on chromosome 6 encoding proteins involved in pattern formation. These proteins contain a characteristic DNA-binding motif called a homeodomain and function in transcriptional regulation. There are four distinct clusters of related genes on chromosomes 2, 6, 11, and 15. The protein encoded by this gene is expressed in rhombomere 2 and is important for hindbrain formation in the early embryo. [provided by RefSeq, Mar 2013]