Mouse Hp activation kit by CRISPRa

CAT#: GA201974

Hp CRISPRa kit - CRISPR gene activation of mouse haptoglobin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hp
• Locus ID: 15439
• Kit Components:

  GA201974G1, Hp gRNA vector 1 in pCas-Guide-CRISPRa

  GA201974G2, Hp gRNA vector 2 in pCas-Guide-CRISPRa

  GA201974G3, Hp gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329965, NM_017370
• Synonyms: HP-1; preHP2
• Summary: This gene encodes a plasma glycoprotein called haptoglobin that binds free hemoglobin. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta subunits that form a disulfide-linked tetrameric protein that plays an important role in the sequestration and clearance of extracorpuscular hemoglobin. Mice lacking the encoded protein exhibit stunted development of lymphoid organs associated with lower counts of mature T and B cells in the blood and secondary lymphoid compartments. [provided by RefSeq, Aug 2016]