Mouse Hsd11b2 activation kit by CRISPRa

CAT#: GA201998

Hsd11b2 CRISPRa kit - CRISPR gene activation of mouse hydroxysteroid 11-beta dehydrogenase 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Hsd11b2
Locus ID 15484
Kit Components

GA201998G1, Hsd11b2 gRNA vector 1 in pCas-Guide-CRISPRa

GA201998G2, Hsd11b2 gRNA vector 2 in pCas-Guide-CRISPRa

GA201998G3, Hsd11b2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_008289
Synonyms 11HSD2
Summary Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.