Mouse Icam2 activation kit by CRISPRa

CAT#: GA202048

Icam2 CRISPRa kit - CRISPR gene activation of mouse intercellular adhesion molecule 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Icam2
• Locus ID: 15896
• Kit Components:

  GA202048G1, Icam2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202048G2, Icam2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202048G3, Icam2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010494
• Synonyms: CD102; Icam-2; Ly-60
• Summary: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. [UniProtKB/Swiss-Prot Function]