Mouse Irf8 activation kit by CRISPRa

CAT#: GA202050

Irf8 CRISPRa kit - CRISPR gene activation of mouse interferon regulatory factor 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Irf8
• Locus ID: 15900
• Kit Components:

  GA202050G1, Irf8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202050G2, Irf8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202050G3, Irf8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301811, NM_008320
• Synonyms: AI893568; ICSBP; Icsbp1; IRF-8; Myls
• Summary: The protein encoded by this gene is a transcription factor that belongs to the interferon regulatory factor family. Proteins belonging to this family have a DNA binding domain at the amino terminus that contains five well-conserved tryptophan-rich repeats. This domain recognizes DNA sequences similar to the interferon-stimulated response element. The protein encoded by this gene promotes or suppresses lineage-specific genes to regulate the differentation of lymphoid and myeloid lineage cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]