Mouse Igfbp2 activation kit by CRISPRa

CAT#: GA202093

Igfbp2 CRISPRa kit - CRISPR gene activation of mouse insulin-like growth factor binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Igfbp2
• Locus ID: 16008
• Kit Components:

  GA202093G1, Igfbp2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202093G2, Igfbp2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202093G3, Igfbp2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001310659, NM_008342
• Synonyms: AI255832; IBP-2; Igfbp-2; mIGFBP-2
• Summary: The protein encoded by this gene is one of several similar proteins that bind insulin-like growth factors I and II (Igf-I and Igf-II). The encoded protein can be secreted into the bloodstream, where it binds Igf-I and Igf-II with high affinity, or it can remain intracellular, interacting with many different ligands. Two transcript variants, one encoding a secreted isoform and the other encoding a nonsecreted isoform, have been found for this gene. [provided by RefSeq, Sep 2015]