Mouse Cd74 activation kit by CRISPRa

CAT#: GA202109

Cd74 CRISPRa kit - CRISPR gene activation of mouse CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cd74
• Locus ID: 16149
• Kit Components:

  GA202109G1, Cd74 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202109G2, Cd74 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202109G3, Cd74 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042605, NM_010545
• Synonyms: CLIP; DHLAG; HLADG; Ia-GAMMA; Ii
• Summary: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. [UniProtKB/Swiss-Prot Function]