Mouse Il12rb1 activation kit by CRISPRa

CAT#: GA202120

Il12rb1 CRISPRa kit - CRISPR gene activation of mouse interleukin 12 receptor, beta 1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Il12rb1
Locus ID 16161
Kit Components

GA202120G1, Il12rb1 gRNA vector 1 in pCas-Guide-CRISPRa

GA202120G2, Il12rb1 gRNA vector 2 in pCas-Guide-CRISPRa

GA202120G3, Il12rb1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_008353
Synonyms CD212; IL-12R[b]
Summary Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.