Mouse Il1a activation kit by CRISPRa

CAT#: GA202132

Il1a CRISPRa kit - CRISPR gene activation of mouse interleukin 1 alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Il1a
• Locus ID: 16175
• Kit Components:

  GA202132G1, Il1a gRNA vector 1 in pCas-Guide-CRISPRa

  GA202132G2, Il1a gRNA vector 2 in pCas-Guide-CRISPRa

  GA202132G3, Il1a gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010554
• Synonyms: Il-1a
• Summary: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [UniProtKB/Swiss-Prot Function]