Mouse Il6ra activation kit by CRISPRa

CAT#: GA202150

Il6ra CRISPRa kit - CRISPR gene activation of mouse interleukin 6 receptor, alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Il6ra
• Locus ID: 16194
• Kit Components:

  GA202150G1, Il6ra gRNA vector 1 in pCas-Guide-CRISPRa

  GA202150G2, Il6ra gRNA vector 2 in pCas-Guide-CRISPRa

  GA202150G3, Il6ra gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001310676, NM_010559
• Synonyms: CD126; IL-6R; IL-6R-alpha; IL-6RA; Il6r
• Summary: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. [UniProtKB/Swiss-Prot Function]