Mouse Itga2 activation kit by CRISPRa

CAT#: GA202192

Itga2 CRISPRa kit - CRISPR gene activation of mouse integrin alpha 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Itga2
• Locus ID: 16398
• Kit Components:

  GA202192G1, Itga2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202192G2, Itga2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202192G3, Itga2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008396
• Synonyms: CD49B; DX5
• Summary: Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis. [UniProtKB/Swiss-Prot Function]