Mouse Fabp5 activation kit by CRISPRa

CAT#: GA202323

Fabp5 CRISPRa kit - CRISPR gene activation of mouse fatty acid binding protein 5, epidermal

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Fabp5
• Locus ID: 16592
• Kit Components:

  GA202323G1, Fabp5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202323G2, Fabp5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202323G3, Fabp5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001272097, NM_001272098, NM_010634
• Synonyms: E-FABP; Fabpe; Klbp; mal1; PA-FABP
• Summary: The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. In humans this gene has been associated with psoriasis and type 2 diabetes. In mouse deficiency of this gene in combination with a deficiency in Fabp4 confers protection against atherosclerosis, diet-induced obesity, insulin resistance and experimental autoimmune encephalomyelitis (the mouse model for multiple sclerosis). Alternative splicing results in multiple transcript variants that encode different protein isoforms. The mouse genome contains many pseudogenes similar to this locus. [provided by RefSeq, Jan 2013]