Mouse Krt19 activation kit by CRISPRa

CAT#: GA202373

Krt19 CRISPRa kit - CRISPR gene activation of mouse keratin 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Krt19
• Locus ID: 16669
• Kit Components:

  GA202373G1, Krt19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202373G2, Krt19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202373G3, Krt19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313963, NM_008471
• Synonyms: AI663979; CK-19; EndoC; K19; Krt-1.19; Krt1-19
• Summary: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]