Mouse Lamp2 activation kit by CRISPRa

CAT#: GA202412

Lamp2 CRISPRa kit - CRISPR gene activation of mouse lysosomal-associated membrane protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Lamp2
• Locus ID: 16784
• Kit Components:

  GA202412G1, Lamp2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202412G2, Lamp2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202412G3, Lamp2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001017959, NM_001290485, NM_010685, NR_152733
• Synonyms: CD107b; Lamp-2; Lamp-2a; Lamp-2b; Lamp-2c; Lamp II; LGP-B; Mac3
• Summary: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. [UniProtKB/Swiss-Prot Function]