Mouse Lif activation kit by CRISPRa

CAT#: GA202458

Lif CRISPRa kit - CRISPR gene activation of mouse leukemia inhibitory factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Lif
• Locus ID: 16878
• Kit Components:

  GA202458G1, Lif gRNA vector 1 in pCas-Guide-CRISPRa

  GA202458G2, Lif gRNA vector 2 in pCas-Guide-CRISPRa

  GA202458G3, Lif gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039537, NM_008501
• Summary: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. [UniProtKB/Swiss-Prot Function]