Mouse Ltc4s activation kit by CRISPRa

CAT#: GA202511

Ltc4s CRISPRa kit - CRISPR gene activation of mouse leukotriene C4 synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ltc4s
• Locus ID: 17001
• Kit Components:

  GA202511G1, Ltc4s gRNA vector 1 in pCas-Guide-CRISPRa

  GA202511G2, Ltc4s gRNA vector 2 in pCas-Guide-CRISPRa

  GA202511G3, Ltc4s gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313968, NM_008521, NR_132732, NR_132733
• Summary: The protein encoded by this gene is an enzyme that catalyzes the synthesis of leukotriene C4 by combining leukotriene A4 with reduced glutathione. The encoded protein is found in the outer nuclear membrane and in the peripheral endoplasmic reticulum. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as bronchial asthma in humans. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]