Mouse Cma1 activation kit by CRISPRa
CAT#: GA202613
Cma1 CRISPRa kit - CRISPR gene activation of mouse chymase 1, mast cell
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Cma1 |
Locus ID | 17228 |
Kit Components | GA202613G1, Cma1 gRNA vector 1 in pCas-Guide-CRISPRa GA202613G2, Cma1 gRNA vector 2 in pCas-Guide-CRISPRa GA202613G3, Cma1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_010780 |
Synonyms | Mcp-5; Mcp5; Mcpt5; MMCP-5 |
Summary | This gene encodes a serine protease that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. The encoded preproprotein undergoes proteolytic processing to generate a functional enzyme with elastase-like activity. Mice lacking the encoded protein exhibit significant attenuation of ischemia-reperfusion injury of the skeletal muscle. This gene is located in a cluster of related mast cell protease genes on chromosome 14. [provided by RefSeq, Nov 2015] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN503506 | Cma1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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