Mouse Mdk activation kit by CRISPRa

CAT#: GA202619

Mdk CRISPRa kit - CRISPR gene activation of mouse midkine

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Mdk
• Locus ID: 17242
• Kit Components:

  GA202619G1, Mdk gRNA vector 1 in pCas-Guide-CRISPRa

  GA202619G2, Mdk gRNA vector 2 in pCas-Guide-CRISPRa

  GA202619G3, Mdk gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012335, NM_001012336, NM_001291481, NM_001291482, NM_001291483, NM_010784
• Synonyms: Mek; MK
• Summary: This gene encodes a secreted growth factor that belongs to the pleiotrophin/midkine heparin-binding protein family and functions in a variety of biological processes. The encoded cytokine promotes the growth, differentiation, survival and migration of several target cells including leucocytes involved in inflammation. This protein plays a role in the formation of scar tissue and intraperitoneal adhesions, and promotes neurite outgrowth and neuron survival. The protein encoded by this gene is associated with obesity and inhibition of insulin signaling in fat cells. A pseudogene of this gene is present on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]