Mouse Mgmt activation kit by CRISPRa
CAT#: GA202654
Mgmt CRISPRa kit - CRISPR gene activation of mouse O-6-methylguanine-DNA methyltransferase
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Mgmt |
Locus ID | 17314 |
Kit Components | GA202654G1, Mgmt gRNA vector 1 in pCas-Guide-CRISPRa GA202654G2, Mgmt gRNA vector 2 in pCas-Guide-CRISPRa GA202654G3, Mgmt gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_008598 |
Synonyms | Agat; AGT; AI267024 |
Summary | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN510068 | Mgmt - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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