Mouse Mitf activation kit by CRISPRa

CAT#: GA202661

Mitf CRISPRa kit - CRISPR gene activation of mouse melanogenesis associated transcription factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Mitf
• Locus ID: 17342
• Kit Components:

  GA202661G1, Mitf gRNA vector 1 in pCas-Guide-CRISPRa

  GA202661G2, Mitf gRNA vector 2 in pCas-Guide-CRISPRa

  GA202661G3, Mitf gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113198, NM_001178049, NM_008601
• Synonyms: BCC2; Bhlhe32; bw; Gsfbcc2; mi; vit; Vitiligo; Wh
• Summary: This transcription factor serves at a critical point between extracellular signaling and downstream targets in cell specification in early eye and neural crest development. Mutant alleles have been identified that generate distinct phenotypes. Some of these alleles are being used to model the human diseases Waardenburg syndrome IIa and Tietz syndrome. [provided by RefSeq, Jul 2008]