Mouse Mmp16 activation kit by CRISPRa

CAT#: GA202680

Mmp16 CRISPRa kit - CRISPR gene activation of mouse matrix metallopeptidase 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Mmp16
• Locus ID: 17389
• Kit Components:

  GA202680G1, Mmp16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202680G2, Mmp16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202680G3, Mmp16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019724, NR_135158
• Synonyms: MT-MMP 3; MT3-MMP; Mt3mmp
• Summary: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit retarded growth of the skeleton, especially in the cranium and long bones. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]