Mouse Ndp activation kit by CRISPRa

CAT#: GA202847

Ndp CRISPRa kit - CRISPR gene activation of mouse Norrie disease (pseudoglioma) (human)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ndp
• Locus ID: 17986
• Kit Components:

  GA202847G1, Ndp gRNA vector 1 in pCas-Guide-CRISPRa

  GA202847G2, Ndp gRNA vector 2 in pCas-Guide-CRISPRa

  GA202847G3, Ndp gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010883
• Synonyms: ND; Ndph
• Summary: This gene encodes a secreted protein that acts a ligand for multiple different receptors and participates in both Wnt and Wnt-independant signalling. Its activity is important in vascular development of the eye and inner ear. Mutation of the related gene in humans causes Norrie syndrome. [provided by RefSeq, May 2015]