Mouse Nf1 activation kit by CRISPRa

CAT#: GA202868

Nf1 CRISPRa kit - CRISPR gene activation of mouse neurofibromin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Nf1
• Locus ID: 18015
• Kit Components:

  GA202868G1, Nf1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202868G2, Nf1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202868G3, Nf1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010897
• Synonyms: AW494271; Dsk9; E030030H24Rik; Mhdadsk9; Nf-1
• Summary: Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. [UniProtKB/Swiss-Prot Function]