Mouse Nppc activation kit by CRISPRa

CAT#: GA202951

Nppc CRISPRa kit - CRISPR gene activation of mouse natriuretic peptide type C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Nppc
• Locus ID: 18159
• Kit Components:

  GA202951G1, Nppc gRNA vector 1 in pCas-Guide-CRISPRa

  GA202951G2, Nppc gRNA vector 2 in pCas-Guide-CRISPRa

  GA202951G3, Nppc gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010933
• Synonyms: CNP; lbab
• Summary: This gene encodes a member of the natriuretic peptide family. Natriuretic peptides are involved in the control of blood pressure, extracellular fluid volume and electrolyte homeostasis. The encoded protein also plays a role in sensory neuron bifurcation, and is a critical regulator of endochondral bone growth. The encoded protein is a ligand for the natriuretic peptide receptor B, and is synthesized as a preprohormone which is cleaved to produce a mature peptide. Mutations in this gene are associated with dwarfism resulting from impaired endochondral ossification. [provided by RefSeq, Apr 2011]