Mouse Ogg1 activation kit by CRISPRa

CAT#: GA203011

Ogg1 CRISPRa kit - CRISPR gene activation of mouse 8-oxoguanine DNA-glycosylase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ogg1
• Locus ID: 18294
• Kit Components:

  GA203011G1, Ogg1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203011G2, Ogg1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203011G3, Ogg1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010957, NR_149720
• Synonyms: Mmh
• Summary: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. [UniProtKB/Swiss-Prot Function]