Mouse Pbx1 activation kit by CRISPRa

CAT#: GA203108

Pbx1 CRISPRa kit - CRISPR gene activation of mouse pre B cell leukemia homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Pbx1
• Locus ID: 18514
• Kit Components:

  GA203108G1, Pbx1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203108G2, Pbx1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203108G3, Pbx1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291508, NM_001291509, NM_008783, NM_183355
• Synonyms: 2310056B04Rik; D230003C07Rik; Pbx-1
• Summary: This gene encodes a homeobox protein that belongs to the three-amino-acid loop extension/Pre-B cell leukemia transcription factor (TALE/PBX) family of proteins. The encoded protein is involved in several biological processes during embryogenesis including steroidogenesis, sexual development and the maintenance of hematopoietic stem cells. This protein functions in the development of several organ systems and plays a role in skeletal patterning and programming. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]