Mouse Penk activation kit by CRISPRa

CAT#: GA203174

Penk CRISPRa kit - CRISPR gene activation of mouse preproenkephalin


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Penk
Locus ID 18619
Kit Components

GA203174G1, Penk gRNA vector 1 in pCas-Guide-CRISPRa

GA203174G2, Penk gRNA vector 2 in pCas-Guide-CRISPRa

GA203174G3, Penk gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001002927, NM_001348209
Synonyms AI326464; ENK; Penk1; PPA
Summary Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(238-259) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.