Mouse Prkaca activation kit by CRISPRa

CAT#: GA203239

Prkaca CRISPRa kit - CRISPR gene activation of mouse protein kinase, cAMP dependent, catalytic, alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Prkaca
• Locus ID: 18747
• Kit Components:

  GA203239G1, Prkaca gRNA vector 1 in pCas-Guide-CRISPRa

  GA203239G2, Prkaca gRNA vector 2 in pCas-Guide-CRISPRa

  GA203239G3, Prkaca gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277898, NM_008854
• Synonyms: Pkaca; PKCD
• Summary: This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AMP levels. This gene encodes the alpha catalytic subunit of protein kinase A. Protein kinase A-mediated signaling is transduced via phosphorylation of target proteins, and is important for many cellular functions, including mammalian sperm maturation and motility. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Apr 2013]