Mouse Pla2g2c activation kit by CRISPRa

CAT#: GA203265

Pla2g2c CRISPRa kit - CRISPR gene activation of mouse phospholipase A2, group IIC

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Pla2g2c
• Locus ID: 18781
• Kit Components:

  GA203265G1, Pla2g2c gRNA vector 1 in pCas-Guide-CRISPRa

  GA203265G2, Pla2g2c gRNA vector 2 in pCas-Guide-CRISPRa

  GA203265G3, Pla2g2c gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008868
• Summary: PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Testis PA2 may be important in the production of prostaglandins, by the release of arachidonic acid, which in turn are necessary for the contractions of the seminiferous tubules and the testicular capsule; they also seem to decrease sperm transit time through the male reproductive tract. [UniProtKB/Swiss-Prot Function]