Mouse Ppp1r1b activation kit by CRISPRa

CAT#: GA203356

Ppp1r1b CRISPRa kit - CRISPR gene activation of mouse protein phosphatase 1, regulatory inhibitor subunit 1B


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Ppp1r1b
Locus ID 19049
Kit Components

GA203356G1, Ppp1r1b gRNA vector 1 in pCas-Guide-CRISPRa

GA203356G2, Ppp1r1b gRNA vector 2 in pCas-Guide-CRISPRa

GA203356G3, Ppp1r1b gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001313970, NM_144828
Synonyms AU040756; DARPP-32; Darpp32
Summary This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders in humans. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.