Mouse Ptafr activation kit by CRISPRa

CAT#: GA203440

Ptafr CRISPRa kit - CRISPR gene activation of mouse platelet-activating factor receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ptafr
• Locus ID: 19204
• Kit Components:

  GA203440G1, Ptafr gRNA vector 1 in pCas-Guide-CRISPRa

  GA203440G2, Ptafr gRNA vector 2 in pCas-Guide-CRISPRa

  GA203440G3, Ptafr gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081211
• Synonyms: PAFR
• Summary: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. Binding of the encoded protein to its phospholipid ligand, platelet-activating factor (PAF), may regulate the inflammatory response and the perception of pain. Homozygous knockout mice for this gene exhibit impaired anaphylactic response, resistance to bacterial infection, and reduced pain-related behavior. [provided by RefSeq, Aug 2015]