Mouse Pten activation kit by CRISPRa

CAT#: GA203446

Pten CRISPRa kit - CRISPR gene activation of mouse phosphatase and tensin homolog


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Pten
Locus ID 19211
Kit Components

GA203446G1, Pten gRNA vector 1 in pCas-Guide-CRISPRa

GA203446G2, Pten gRNA vector 2 in pCas-Guide-CRISPRa

GA203446G3, Pten gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_008960
Synonyms 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; MMAC1; TEP1
Summary This gene encodes a phosphatase with dual activity against phospholipids and proteins, and acts as a tumor-suppressor. The protein contains four structural domains, a PIP2-binding domain, a catalytic tensin-type phosphatase domain, a C2 tensin-type domain and a PDZ-binding domain. The protein belongs to the protein tyrosine phosphatase family. Deletion of this gene in mice contribute to tumorigenesis in multiple tissues. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.