Mouse Ptger1 activation kit by CRISPRa

CAT#: GA203451

Ptger1 CRISPRa kit - CRISPR gene activation of mouse prostaglandin E receptor 1 (subtype EP1)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ptger1
• Locus ID: 19216
• Kit Components:

  GA203451G1, Ptger1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203451G2, Ptger1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203451G3, Ptger1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013641
• Synonyms: 42kDa; EP1; Ptgerep1
• Summary: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. [UniProtKB/Swiss-Prot Function]