Mouse Rac2 activation kit by CRISPRa

CAT#: GA203544

Rac2 CRISPRa kit - CRISPR gene activation of mouse Rac family small GTPase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rac2
• Locus ID: 19354
• Kit Components:

  GA203544G1, Rac2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203544G2, Rac2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203544G3, Rac2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009008
• Synonyms: AI323801; AI452260
• Summary: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase. [UniProtKB/Swiss-Prot Function]