Mouse Rad51d activation kit by CRISPRa

CAT#: GA203554

Rad51d CRISPRa kit - CRISPR gene activation of mouse RAD51 paralog D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rad51d
• Locus ID: 19364
• Kit Components:

  GA203554G1, Rad51d gRNA vector 1 in pCas-Guide-CRISPRa

  GA203554G2, Rad51d gRNA vector 2 in pCas-Guide-CRISPRa

  GA203554G3, Rad51d gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277938, NM_001277939, NM_001277941, NM_001277942, NM_011235, NR_102717, NR_102718, NR_102719, NR_102720
• Synonyms: R51H3; Rad51l3; TRAD; Trad-d5
• Summary: This gene belongs to the Rad51 gene family whose products play a major role in homologous recombination and DNA repair. The encoded protein interacts with other proteins of this family, including Rad51b, Rad51c and Xrcc2, and plays an essential role in both DNA repair and telomere maintenance. In humans, germline mutations in this gene may be associated with predisposition to ovarian cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]