Mouse Reg3g activation kit by CRISPRa

CAT#: GA203606

Reg3g CRISPRa kit - CRISPR gene activation of mouse regenerating islet-derived 3 gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Reg3g
• Locus ID: 19695
• Kit Components:

  GA203606G1, Reg3g gRNA vector 1 in pCas-Guide-CRISPRa

  GA203606G2, Reg3g gRNA vector 2 in pCas-Guide-CRISPRa

  GA203606G3, Reg3g gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011260
• Synonyms: AI449515; REG-3-gamma; reg III-gamma
• Summary: This gene encodes a C-type lectin that demonstrates bactericidal activity. This gene is predominantly expressed in the distal small intestine where the encoded protein undergoes proteolytic processing by trypsin. Mice lacking the encoded protein exhibit altered mucus distribution, increased bacterial contact with the epithelium, and elevated inflammatory markers in the ileum, and low-grade inflammation. [provided by RefSeq, Jun 2016]