Mouse Rlbp1 activation kit by CRISPRa

CAT#: GA203644

Rlbp1 CRISPRa kit - CRISPR gene activation of mouse retinaldehyde binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rlbp1
• Locus ID: 19771
• Kit Components:

  GA203644G1, Rlbp1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203644G2, Rlbp1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203644G3, Rlbp1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173483, NM_020599, NM_001357450
• Synonyms: 3110056M11Rik; CRALBP
• Summary: Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. [UniProtKB/Swiss-Prot Function]