Mouse Mst1r activation kit by CRISPRa

CAT#: GA203672

Mst1r CRISPRa kit - CRISPR gene activation of mouse macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Mst1r
• Locus ID: 19882
• Kit Components:

  GA203672G1, Mst1r gRNA vector 1 in pCas-Guide-CRISPRa

  GA203672G2, Mst1r gRNA vector 2 in pCas-Guide-CRISPRa

  GA203672G3, Mst1r gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001287261, NM_009074, NR_109782
• Synonyms: CD136; CDw136; Fv-2; Fv2; PTK8; Ron; STK
• Summary: This gene encodes a precursor protein that is proteolytically cleaved to yield an alpha chain and a beta chain which form a membrane-spanning heterodimer. The encoded protein belongs to a family of cell-surface receptor tyrosine kinases involved in signaling from the cell surface to the intracellular environment. The binding of the encoded protein to its ligand, macrophage-stimulating protein, mediates several biological activities including wound healing, tumor immunity, macrophage activation and hematopoiesis as well as cell growth, motility, survival and adhesion. The protein encoded by this gene also functions in early development and the macrophage-mediated inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].