Mouse Sag activation kit by CRISPRa

CAT#: GA203758

Sag CRISPRa kit - CRISPR gene activation of mouse S-antigen, retina and pineal gland (arrestin)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sag
• Locus ID: 20215
• Kit Components:

  GA203758G1, Sag gRNA vector 1 in pCas-Guide-CRISPRa

  GA203758G2, Sag gRNA vector 2 in pCas-Guide-CRISPRa

  GA203758G3, Sag gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009118
• Synonyms: A930001K18Rik; Arr1; arrestin; Irbp
• Summary: Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. [UniProtKB/Swiss-Prot Function]