Mouse Cxcl5 activation kit by CRISPRa

CAT#: GA203812

Cxcl5 CRISPRa kit - CRISPR gene activation of mouse chemokine (C-X-C motif) ligand 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cxcl5
• Locus ID: 20311
• Kit Components:

  GA203812G1, Cxcl5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203812G2, Cxcl5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203812G3, Cxcl5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009141
• Synonyms: AMCF-II; Cxcl6; ENA-78; GCP-2; LIX; Scyb5; Scyb6
• Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013]