Mouse Sfrp2 activation kit by CRISPRa

CAT#: GA203818

Sfrp2 CRISPRa kit - CRISPR gene activation of mouse secreted frizzled-related protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sfrp2
• Locus ID: 20319
• Kit Components:

  GA203818G1, Sfrp2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203818G2, Sfrp2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203818G3, Sfrp2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009144
• Synonyms: AI851596; Sdf5
• Summary: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. [UniProtKB/Swiss-Prot Function]