Mouse Sftpd activation kit by CRISPRa

CAT#: GA203862

Sftpd CRISPRa kit - CRISPR gene activation of mouse surfactant associated protein D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sftpd
• Locus ID: 20390
• Kit Components:

  GA203862G1, Sftpd gRNA vector 1 in pCas-Guide-CRISPRa

  GA203862G2, Sftpd gRNA vector 2 in pCas-Guide-CRISPRa

  GA203862G3, Sftpd gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009160
• Synonyms: AI573415; Sfpd; Sftp4; SP-D
• Summary: Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. [UniProtKB/Swiss-Prot Function]