Mouse Sgca activation kit by CRISPRa

CAT#: GA203863

Sgca CRISPRa kit - CRISPR gene activation of mouse sarcoglycan, alpha (dystrophin-associated glycoprotein)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sgca
• Locus ID: 20391
• Kit Components:

  GA203863G1, Sgca gRNA vector 1 in pCas-Guide-CRISPRa

  GA203863G2, Sgca gRNA vector 2 in pCas-Guide-CRISPRa

  GA203863G3, Sgca gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136080, NM_009161
• Synonyms: 50DAG; 59kDa; adhalin; Asg
• Summary: This gene encodes a member of the sarcoglycan alpha/epsilon family of transmembrane proteins. The encoded protein is part of the dystrophin-glycoprotein complex which links the extracellular matrix to the cytoskeleton in muscle fibers. Disruption of this gene results in progressive muscular dystrophy and is associated with the development of embryonal rhabdomysarcoma. [provided by RefSeq, Dec 2012]