Mouse St6gal1 activation kit by CRISPRa

CAT#: GA203891

St6gal1 CRISPRa kit - CRISPR gene activation of mouse beta galactoside alpha 2,6 sialyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: St6gal1
• Locus ID: 20440
• Kit Components:

  GA203891G1, St6gal1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203891G2, St6gal1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203891G3, St6gal1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252505, NM_001252506, NM_145933
• Synonyms: AW742324; Siat1; St6gal; St6Gal-I; St6galI
• Summary: This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Nov 2011]