Mouse St3gal1 activation kit by CRISPRa

CAT#: GA203893

St3gal1 CRISPRa kit - CRISPR gene activation of mouse ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: St3gal1
• Locus ID: 20442
• Kit Components:

  GA203893G1, St3gal1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203893G2, St3gal1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203893G3, St3gal1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009177
• Synonyms: 5330418N22Rik; AI467004; Siat4; Siat4a; St3gal-1; ST3GalI
• Summary: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. [UniProtKB/Swiss-Prot Function]