Mouse Skil activation kit by CRISPRa

CAT#: GA203921

Skil CRISPRa kit - CRISPR gene activation of mouse SKI-like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Skil
• Locus ID: 20482
• Kit Components:

  GA203921G1, Skil gRNA vector 1 in pCas-Guide-CRISPRa

  GA203921G2, Skil gRNA vector 2 in pCas-Guide-CRISPRa

  GA203921G3, Skil gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039090, NM_001271772, NM_011386
• Synonyms: Skir; sno; SnoN
• Summary: This gene encodes a member of a small family of proteins that play a key role in the response of cells to extracellular growth signals. The encoded protein regulates members of the transforming growth factor beta signaling pathway. It is highly expressed in certain cancer cells, where it may have both tumor-suppressing and tumor-promoting roles. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]