Mouse Sstr2 activation kit by CRISPRa

CAT#: GA203992

Sstr2 CRISPRa kit - CRISPR gene activation of mouse somatostatin receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sstr2
• Locus ID: 20606
• Kit Components:

  GA203992G1, Sstr2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203992G2, Sstr2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203992G3, Sstr2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042606, NM_009217
• Synonyms: Smstr-2; Smstr2; SRIF-1; SS2R; sst2; SSTR-2
• Summary: The protein encoded by this gene is a receptor for somatostatin, which acts at many sites to inhibit the release of several hormones and other secretory proteins. The encoded protein is a member of the superfamily of receptors having seven transmembrane segments and is involved in many processes, including adenylyl cyclase inhibition, phosphotyrosine phosphatase stimulation, and inhibition of calcium entry and cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]